产品货号：
Z12517
中文名称：
CCR3抗体
英文名称：
Anti-CCR3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CCR3 Antibody |
| 指标别名 | C C chemokine receptor type 3;C C CKR 3;CC CKR 3;CCR 3;CCR3;CD193;CKR3;CMKBR3;Eosinophil eotaxin receptor |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC |
| 基因名称 | CCR3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human CCR3(1-20aa MTTSLDTVETFGTTSYYDDV). |
| 实际分子量 | 55KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | C-C chemokine receptor type 3,also called CCR3 or CKR3 is a protein that in humans is encoded by the CCR3 gene.The protein encoded by this gene is a receptor for C-C type chemokines.It belongs to family 1 of the G protein-coupled receptors.This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21.This receptor binds and responds to a variety of chemokines,including eotaxin(CCL11),eotaxin-3(CCL26),MCP-3(CCL7),MCP-4(CCL13),and RANTES(CCL5).It is highly expressed in eosinophils and basophils,and is also detected in TH1 and TH2 cells,as well as in airway epithelial cells.This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway.It is also known to be an entry co-receptor for HIV-1.Alternatively spliced transcript variants have been described. |
| Uniprot ID | P51677 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | chemokine(C-C motif) receptor 3 |
| 蛋白名全称 | C-C chemokine receptor type 3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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